People with a gene variant that puts them at high risk for Alzheimer's disease are protected from its debilitating effects if they also carry a variant of a completely different gene, Stanford University School of Medicine ...
Apr 13, 2020
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For a person with Alzheimer's disease, there's no turning back the clock. By the time she begins to experience memory loss and other worrisome signs, cognitive decline has already set in. And decades of clinical trials have ...
Nov 19, 2019
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A study carried out with a new human stem cell-derived model reveals that the most prevalent genetic risk factor of Alzheimer's disease (AD), apolipoprotein E4 (APOE4), impairs the function of human brain immune cells, microglia. ...
Sep 16, 2019
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Adults carrying a gene associated with a higher risk of Alzheimer's disease had a harder time accessing recently acquired knowledge, even though they didn't show any symptoms of memory problems, according to findings published ...
Aug 22, 2019
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An experimental drug known as A03, which was previously developed to treat depression, increases the levels of the enzyme Sirtuin1, or SirT1, and improves memory in mice. The mice were genetically modified to have a protein ...
Dec 21, 2018
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ApoE4, a protein linked to both Alzheimer's disease and a form of dementia caused by damage of blood vessels in the brain, increases the risk of cognitive impairment by reducing the number and responsiveness of blood vessels ...
Sep 20, 2018
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Greater aortic stiffness is related to lower cerebral blood flow, especially among individuals with increased genetic predisposition to Alzheimer's disease, according to research from Vanderbilt University Medical Center.
Aug 31, 2018
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People with a gene variant called APOE4 have a higher risk of developing late-onset Alzheimer's disease: APOE4 is three times more common among Alzheimer's patients than it is among the general population. However, little ...
May 31, 2018
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Last year, Barbara's husband thought it would be fun to learn more about their family's history, so he bought 23andMe gene-testing kits for himself, Barbara and their three daughters for Christmas.
Dec 22, 2017
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For decades, scientists have known that people with two copies of a gene called apolipoprotein E4 (ApoE4) are much more likely to have Alzheimer's disease at age 65 than the rest of the population. Now, researchers at the ...
Aug 17, 2016
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