Research just carried out in the Immunology Research Centre, led by Dr James Harris, based in the School of Biochemistry and Immunology, Trinity College Dublin, shows that the process of autophagy regulates the production ...
Oct 24, 2012
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Times of distress literally eat away at the core of starving cells: They start to digest their own parts and recycle them for metabolic purposes. Ingo Schmitz at the Helmholtz Centre for Infection Research in Braunschweig, ...
Oct 12, 2012
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Researchers at Moffitt Cancer Center and colleagues at the University of South Florida and Wayne State University have discovered that tumor cell survival relies on adaptation to acidic conditions in the tumor microenvironment. ...
Sep 6, 2012
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The body has a built-in system known as autophagy, or 'self-eating,' that controls how cells live or die. Deregulation of autophagy is linked to the development of human diseases, including neural degeneration and cancer.
Aug 1, 2012
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Researchers at Georgetown Lombardi Comprehensive Cancer Center have uncovered a single molecule they say is a major determinant of resistance to anti-estrogen therapy used to treat or prevent breast cancer in high-risk women.
Jul 2, 2012
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Scientists at Washington University School of Medicine in St. Louis have found new clues to why some urinary tract infections recur persistently after multiple rounds of treatment.
Jun 18, 2012
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A new finding in basic science should trigger a "change in thinking" about how cancer drugs might be developed and tested for maximum effectiveness, says Louis M. Weiner, M.D., director of the Georgetown Lombardi Comprehensive ...
Mar 21, 2012
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Cells use various methods to break down and recycle worn-out components—autophagy is one of them. In the dissertation she will be defending at Umea University in Sweden, Karin Håberg shows that the protein SNX18 ...
Feb 27, 2012
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Blocking autophagy -- the process of "self-eating" within cells -- is turning out to be a viable way to enhance the effectiveness of a wide variety of cancer treatments.
Feb 19, 2012
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Researchers at the RIKEN Brain Science Institute (BSI) have discovered a key mechanism responsible for selectively degrading aggregates of ubiquitinated proteins from the cell. Their findings indicate that the capture and ...
Nov 7, 2011
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