Gerontology & Geriatrics

Bone and muscle health can 'make or break' care as we age

Experts at a prestigious medical conference hosted by the American Geriatrics Society (AGS) and funded by the National Institutes of Health's (NIH's) National Institute on Aging (NIA) hope their work—reported this week ...

Health

Serum IL-35 levels tied to bone loss with rheumatoid arthritis

Serum interleukin (IL)-35 levels are associated with bone loss and may represent a novel therapeutic target for postmenopausal women with rheumatoid arthritis (RA), according to a study published online Aug. 26 in Mediators ...

Health

Vitamin D: How much is too much of a good thing?

When bare skin is exposed to sunlight, it makes Vitamin D, which is needed by our bodies to absorb calcium and ensure strong, healthy bones. With bathing suit skin exposure, it only takes about 10-15 minutes of sun exposure ...

Medical research

Why do bones fail?

Can analytical methods from materials science help researchers better understand human bones? A team at Empa in Thun is pursuing precisely this approach.

Diseases, Conditions, Syndromes

Osteoporosis drugs linked to reduced risk of premature death

Two studies led by the Garvan Institute of Medical Research have revealed that nitrogen-bisphosphonates, drugs commonly prescribed for osteoporosis, reduced the risk of premature mortality by 34% in a cohort of over 6,000 ...

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Osteoporosis

Osteoporosis is a disease of bone that leads to an increased risk of fracture. In osteoporosis the bone mineral density (BMD) is reduced, bone microarchitecture is disrupted, and the amount and variety of non-collagenous proteins in bone is altered. Osteoporosis is defined by the World Health Organization (WHO) in women as a bone mineral density 2.5 standard deviations below peak bone mass (20-year-old healthy female average) as measured by DXA; the term "established osteoporosis" includes the presence of a fragility fracture. Osteoporosis is most common in women after menopause, when it is called postmenopausal osteoporosis, but may also develop in men, and may occur in anyone in the presence of particular hormonal disorders and other chronic diseases or as a result of medications, specifically glucocorticoids, when the disease is called steroid- or glucocorticoid-induced osteoporosis (SIOP or GIOP). Given its influence is the risk of fragility fracture, osteoporosis may significantly affect life expectancy and quality of life.

Osteoporosis can be prevented with lifestyle changes and sometimes medication; in people with osteoporosis, treatment may involve both. Lifestyle change includes preventing falls and exercise; medication includes calcium, vitamin D, bisphosphonates and several others. Fall-prevention advice includes exercise to tone deambulatory muscles, proprioception-improvement exercises; equilibrium therapies may be included. Exercise with its anabolic effect, may at the same time stop or reverse osteoporosis.

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