Medical research

Mapping human brain development

The human brain is probably the most complex organ in the entire living world and has long been an object of fascination for researchers. However, studying the brain, and especially the genes and molecular switches that regulate ...

Medical research

Modular approach found to improve consistency of organoids

(Medical Xpress)—A team of researchers from the U.S. and Australia working at the Yale Stem Cell Center report that they have met with some success in improving the usefulness of organoids. In their paper published in the ...

Medications

Brain organoids with the potential to predict drug permeability

The human brain is bathed in a supportive fluid called the cerebrospinal fluid (CSF) that provides nutrients and is required for proper brain function. The composition of human CSF and how it is made are poorly understood ...

Genetics

Probing the genes that organize early brain development

When brains begin developing, there are a lot of moving parts—and when mutations happen in early neurodevelopment, it can lead to disorders like macrocephaly and autism. But scientists don't know much about the ways that ...

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