The brain changes that occur at the onset of psychiatric conditions such as schizophrenia and bipolar disorder could originate from a disturbance in neuronal signaling pathways during brain development, RIKEN neuroscientists ...
Oct 30, 2020
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When brains begin developing, there are a lot of moving parts—and when mutations happen in early neurodevelopment, it can lead to disorders like macrocephaly and autism. But scientists don't know much about the ways that ...
Mar 11, 2020
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Measuring just a few millimeters across, clusters of cultured cells that self-assemble into three-dimensional structures may look like just tiny blobs. But these tissues, called organoids, are enabling scientists to study ...
Sep 15, 2020
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Brain organoids—three-dimensional balls of brain-like tissue grown in the lab, often from human stem cells—have been touted for their potential to let scientists study the formation of the brain's complex circuitry in ...
Jan 29, 2020
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Vanderbilt University engineering researchers took a major step toward building a "brain in a dish:" They cultured induced pluripotent stem cells into a successful three-dimensional blood-brain barrier model.
Feb 22, 2019
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A team of medical researchers at the University of Tübingen's Hertie Institute for Clinical Brain Research in Germany has found that exposing organoids at a certain stage of growth to interleukin-6 leads to an increase in ...
SARS-CoV-2 can infect human neural progenitor cells and brain organoids, as shown by researchers from the Shenzhen Institutes of Advanced Technology (SIAT) of the Chinese Academy of Sciences and their collaborators from The ...
Aug 25, 2020
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Most autism spectrum disorders have a complex, multifactorial genetic component, making it difficult to find specific treatments. Rett syndrome is an exception. Babies born with this form of the disorder have mutations specifically ...
Dec 8, 2020
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Researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have developed brain organoids—3D, brain-like structures grown from human stem cells—that show organized waves of ...
Aug 23, 2021
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As research involving the transplantation of human "mini-brains"—known as brain organoids—into animals to study disease continues to expand, so do the ethical debates around the practice. One concern is the possibility, ...
Oct 14, 2019
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