Many childhood cancers start with a hijacking at the molecular level. A group of abnormal proteins known as fusion proteins aberrantly engages with a collection of proteins that switches genes on and off. As a result, genes ...
Mar 6, 2024
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Chimeric antigen receptor (CAR)-T cell therapy is a potent emerging weapon against cancer, altering patients' T cells so they can better find and destroy tumor cells. But CAR-T cell therapy doesn't work well in every cancer—including ...
Mar 1, 2024
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Drug discovery can be a frustrating process of trial and error. Scientists using fragment-based drug discovery link fragments of different molecules together to create a more potent drug but may not know whether a compound ...
Feb 28, 2024
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Scientists at City of Hope, one of the largest cancer research and treatment organizations in the United States, have devised an innovative approach to target and destroy hard-to-kill leukemia stem cells. The journal Blood ...
Feb 26, 2024
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A UC Davis Health study found that a single dose of Bacillus Calmette-Guérin (BCG), the vaccine for tuberculosis (TB), reduced liver tumor burden and extended the survival of mice with liver cancer. The study, published ...
Feb 21, 2024
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New research by the University of Sussex could help to increase life expectancy and improve treatment for an aggressive brain cancer, which impacts thousands of people every year in the UK, and hundreds of thousands worldwide.
Feb 15, 2024
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A potential new drug to prevent Alzheimer's disease in people with the so-called Alzheimer's gene has been discovered by a University of Arkansas for Medical Sciences (UAMS) research team led by Sue Griffin, Ph.D.
Feb 6, 2024
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In a major step forward in drug development, researchers at the National Institute of Standards and Technology (NIST) have developed a tool for building a system known as heart-on-a-chip (HoC).
Feb 6, 2024
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Italian scientists from Università Cattolica at Rome have discovered an important genetic mechanism that pancreatic cancer cells employ to evade therapies, paving the way to new drugs for a killer disease. The tumor evades ...
Feb 6, 2024
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Monash University-led research is using math to predict how new combination therapies can help patients with breast cancer who no longer respond to conventional therapies.
Feb 5, 2024
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