Mutations in a genetic region that regulates RNA stability could influence prostate cancer outcomes and drug resistance, according to new work from scientists at Fred Hutchinson Cancer Center published in Cell Reports.
Aug 7, 2023
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For many years, the human genome was viewed as a book of life in which sections of great eloquence and economy of expression were interspersed with vast stretches of gibberish. The legible sections contained the code for ...
Jun 13, 2022
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Inside cells DNA is tightly wrapped around proteins and packed in a complex, 3-D structure called chromatin. Chromatin not only protects genetic material from damage, but also organizes the entire genome by regulating the ...
Jan 29, 2019
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No one wants to hear that they have a mutation in their DNA associated with the development of cancer. But it may be even more difficult to accept that, in many cases, clinicians can't say whether or by how much that mutation ...
Jun 27, 2017
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Batman and Robin. Sherlock Holmes and Dr. Watson. Fiction is full of dynamic duos that work together to accomplish amazing feats. When one partner is out of commission, the other steps in to make sure the job gets done. But ...
May 31, 2017
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Scientists at The Wistar Institute have unveiled part of the protein complex that protects telomeres—the ends of our chromosomes. The study, published online in Nature Communications, explains how a group of genetic mutations ...
Apr 11, 2017
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Researchers long have known that some portion of the risk of developing cancer is hereditary and that inherited genetic errors are very important in some tumors but much less so in others.
Dec 22, 2015
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Researchers at University of Helsinki, Finland, and Karolinska Institutet, Sweden, discovered previously uncharacterized mutational patterns in the human regulatory genome, especially in gastrointestinal tract cancers.
Jun 8, 2015
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Normal skin contains an unexpectedly high number of cancer-associated mutations, according to a study published in Science. The findings illuminate the first steps cells take towards becoming a cancer and demonstrate the ...
May 21, 2015
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Research conducted at the Florida campus of The Scripps Research Institute (TSRI) has discovered links between a set of genes known to promote tumor growth and mucoepidermoid carcinoma, an oral cancer that affects the salivary ...
Jul 28, 2014
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