The WTX gene is mutated in approximately 30 percent of Wilms tumors, a pediatric kidney cancer. Like many genes, WTX is part of a family. In this case, WTX has two related siblings, FAM123A and FAM123C. While cancer researchers ...
Aug 30, 2012
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Molecular simulations on the JUWELS supercomputer show how the HIV-1 virus is able to evade the human immune system. The newly discovered mechanism could prove to be the Achilles' heel of the virus and open new doors for ...
Feb 28, 2024
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About one third of patients with diabetes mellitus (DM) develop diabetic retinopathy (DR), a leading cause of blindness in working-age individuals. DR typically develops after many years of DM, and some patients do not develop ...
Nov 29, 2022
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With the end of the pandemic seemingly nowhere in sight, scientists are still very focused on finding new or alternative drugs to treat and stop the spread of COVID-19. In a first-of-its-kind study, researchers at the University ...
Jun 22, 2022
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Modern immunotherapeutic anti-cancer drugs support a natural mechanism of the immune system to inhibit the growth of cancer cells. They dock onto a specific receptor of the killer cell and prevent it from being switched off ...
Feb 3, 2021
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Osteoporosis is a disease in which bone loses mass as a result of age or other influences. This weakening is the leading cause of fractures in the elderly, often after trivial injuries, and makes treating these "pathological ...
Oct 8, 2020
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New research from North Carolina State University provides insights into the earliest stages of Angelman syndrome. The work also demonstrates how human cerebral organoids can be used to shed light on genetic disorders that ...
Sep 10, 2020
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Hematopoiesis can be affected by biological stresses, such as infection, inflammation and certain medications. In a new study, researchers from Tokyo Medical and Dental University (TMDU) identified a novel cell surface marker ...
Jul 1, 2020
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Researchers at The Wistar Institute have described the role of mitochondrial fission factor (MFF) in controlling survival of cancer cells, suggesting the protein could represent a promising therapeutic target. They also found ...
Sep 19, 2019
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To successfully set off disease, rotavirus, a virus that causes severe diarrhea and vomiting in children around the world, must invade cells of the gastrointestinal track and trigger a surge of calcium inside the cells. How ...
Jul 25, 2019
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