Oncology & Cancer

New inhibitor blocks the oncogenic protein KRAS

One of the major goals in the development of anti-cancer treatments is to find an inhibitor effective against the oncogenic protein known as KRAS. Despite decades of active agent research, efforts to intercede in this protein's ...

Medical research

The flexible tail of the prion protein poisons brain cells

For decades, there has been no answer to the question of why the altered prion protein is poisonous to brain cells. Neuropathologists from the University of Zurich and University Hospital Zurich have now shown that it is ...

Medical research

Scientists find 3D structure of key drug target for diabetes

An international team led by scientists at The Scripps Research Institute (TSRI) has determined and analyzed the three-dimensional atomic structure of the human glucagon receptor. The receptor, found mainly on liver and kidney ...

Oncology & Cancer

Researchers identify potential biomarker for cancer diagnosis

Scientists studying cancer development have known about micronuclei for some time. These erratic, small extra nuclei, which contain fragments, or whole chromosomes that were not incorporated into daughter cells after cell ...

Medical research

Cholesterol sets off chaotic blood vessel growth

A study at the University of California, San Diego School of Medicine identified a protein that is responsible for regulating blood vessel growth by mediating the efficient removal of cholesterol from the cells. Unregulated ...

Medical research

Study uses Botox to find new wrinkle in brain communication

National Institutes of Health researchers used the popular anti-wrinkle agent Botox to discover a new and important role for a group of molecules that nerve cells use to quickly send messages. This novel role for the molecules, ...

Medical research

Study reveals natural process that blocks viruses

The human body has the ability to ward off viruses by activating a naturally occurring protein at the cellular level, setting off a chain reaction that disrupts the levels of cholesterol required in cell membranes to enable ...

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