A biomedical startup that licensed a Purdue University technology has developed a late-stage prostate cancer therapy that could provide an alternative to current hormone therapies that are known to develop resistance after ...
Oct 13, 2016
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Type 1 (insulin-dependent) diabetes appears to increase the risk of heart disease, the leading cause of death among people with high blood sugar, partly by stimulating the production of calprotectin, a protein that sparks ...
May 7, 2013
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Inhibiting telomerase, an enzyme that rescues malignant cells from destruction by extending the protective caps on the ends of chromosomes, kills tumor cells but also triggers resistance pathways that allow cancer to survive ...
Feb 21, 2012
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Researchers at Rush University Medical Center are conducting an early phase clinical trial of a novel drug therapy for patients with dementia due to Alzheimer's disease. The drug is a new compound called MSDC-0160, which ...
Feb 15, 2012
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Cancer cells are chameleons. They completely change their metabolism to grow continuously. University of Basel scientists have discovered that high levels of the amino acid arginine drive metabolic reprogramming to promote ...
Oct 6, 2023
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As part of their ongoing research on the physiologic factors that contribute to the development of obesity, Joslin Diabetes Center scientists have identified a cell cycle transcriptional co-regulator – TRIP-Br2 – that ...
Jan 6, 2013
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An article published in the journal Nature Communications describes a specific metabolic adaptation in some patients with acute myeloid leukemia affected by tandem mutations in the FLT3 gene. The findings, which could shed ...
Jul 13, 2022
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The mechanisms by which obesity leads towards metabolic co-morbidities, such as diabetes mellitus, are poorly understood and of great public health interest. A study led by Matej Oresic from VTT Technical Research Centre ...
Jun 7, 2011
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Scientists at the Gladstone Institutes have discovered an unusual regulator of body weight and the metabolic syndrome: a molecular mechanism more commonly associated with brain cells. Lowering levels of P75 neurotrophin receptor ...
Jan 12, 2016
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Tracing the metabolism of tumor cells using magnetic resonance imaging (MRI) has not been feasible in routine clinical settings hitherto. Now, an interdisciplinary research team including the Technical University of Munich ...
Nov 10, 2022
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