Immunology

Outsourcing is a matter of time

Immune cells found in the mouse kidney at various stages of development are morphologically virtually indistinguishable. It now turns out that these cells are derived from different tissue sources at different stages in the ...

Medical research

In fighting gut infections, nervous system is key, team finds

The peaceful and delicate co-existence of friendly gut bacteria and the immune system relies on highly coordinated information exchange between immune system cells and certain cells lining the intestine. Until now, scientists ...

Obstetrics & gynaecology

Progesterone from an unexpected source may affect miscarriage risk

About twenty percent of confirmed pregnancies end in miscarriage, most often in the first trimester, for reasons ranging from infection to chromosomal abnormality. But some women have recurrent miscarriages, a painful process ...

Medical research

How signalling proteins affect wound healing

What do a scraped knee, a paper cut, or any form of surgery have in common? The short answer is a wound in need of healing—but the long answer lies in a series of biological activities that allow tissues to repair themselves.

Oncology & Cancer

Researchers identify immune-suppressing target in glioblastoma

Researchers at The University of Texas MD Anderson Cancer Center have identified a tenacious subset of immune macrophages that thwart treatment of glioblastoma with anti-PD-1 checkpoint blockade, elevating a new potential ...

Oncology & Cancer

Scientists discover a new mechanism in childhood kidney cancer

As an embryo develops, its cells must learn what to do with the thousands of genes they've been equipped with. That's why each cell comes with a detailed gene-expression manual outlining exactly which genes should be switched ...

Oncology & Cancer

New software tool uses AI to help doctors identify cancer cells

UT Southwestern researchers have developed a software tool that uses artificial intelligence to recognize cancer cells from digital pathology images—giving clinicians a powerful way of predicting patient outcomes.

Neuroscience

Three types of cells help the brain tell day from night

Bright light at night interrupts the body's normal day-night cycles, called circadian rhythms, and can trigger insomnia. In fact, circadian rhythms play a major role in health. Disrupted day-night cycles have even been linked ...

Neuroscience

Consistent gene changes in Alzheimer's disease across studies

A comparison of mouse Alzheimer's disease models shows changes in the number of cells and the genes they express remain consistent throughout all stages of the disease. The new research published in eNeuro could reveal new ...

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Cell type

A cell type is a distinct morphological or functional form of cell. When a cell switches state from one cell type to another, it undergoes cellular differentiation. A complete list of distinct cell types in the adult human body may include about 210 distinct types.

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