Neuroscience

How is puberty onset developmentally programmed?

The hypothalamus, one of the most complex brain regions in the mammalian nervous system, contains an astonishing heterogeneity of neurons that regulate endocrine, autonomic and behavioral functions. It not only regulates ...

Health

Drug attenuates weight gain in animals fed a high-fat diet

A drug originally developed to treat bacterial infections has proved capable of boosting the metabolism and attenuating the weight gain induced by a fatty diet in tests with mice. The study was conducted at the University ...

Genetics

A brighter future for infertility treatment: study

(Medical Xpress) -- Male infertility could soon have a boost through new treatments at a sub-DNA 'epigenetic' level, according to researchers from The Australian National University.

Medical research

Stem cell breakthrough heralds new era of therapy development

Scientists at the Universities of Glasgow and Southampton have uncovered a new method for culturing adult stem cells which could lead to the creation of revolutionary stem cell therapies for conditions such as arthritis, ...

Oncology & Cancer

Cell signaling targets in leukemia

Mutations in the enzyme IDH (isocitrate dehydrogenase) are found in 15–20% of acute myeloid leukemia (AML) cases. IDH mutations have been shown to impact cellular differentiation and DNA and histone methylation, but little ...

Oncology & Cancer

Nanosecond pulsed electric fields activate immune cells

Nanosecond pulsed electric fields (nsPEFs) produce strong electrical effects by focusing a high powered electrical pulse over a very short period of time. They are attracting attention as a method of physically stimulating ...

Medical research

Signals from skin cells control fat cell specialization

Cells can change to a more specialized type in a process called cellular differentiation. Scientists have revealed that protein secretions by skin cells known as keratinocytes control the differentiation of subsurface skin ...

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