Oncology & Cancer

Cancer biology: Keeping bad company

The p53 tumor suppressor protein manages DNA repair mechanisms in response to genetic damage and kills off precancerous cells before they multiply. The loss of p53 due to mutation greatly increases risk of tumorigenesis. ...

Genetics

In cancer, an embryonic gene-silencing mechanism gone awry

There are some genes that are only activated in the very first days of an embryo's existence. Once they have accomplished their task, they are shut down forever, unlike most of our genes, which remain active throughout our ...

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