Chemically modified inhibitors of the COX-2 enzyme relieve anxiety behaviors in mice by activating natural "endocannabinoids" without gastrointestinal side effects, Vanderbilt University scientists will report next week.
Aug 4, 2013
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Relapses in a common form of leukemia may be preventable following new research that has identified how the cancer develops resistance to first line treatments.
Apr 9, 2024
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The advent of small-molecule targeted therapies, a decade ago, revolutionized the treatment of metastatic melanoma, provided that the tumors carry the mutations to respond to these treatments. However, despite a remarkable ...
Sep 22, 2022
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EPFL scientists have discovered how an anti-cancer drug could be repurposed to improve memory. It does so by supporting the cell's ability to read the very genes that are important for learning. The epigenetic mechanism of ...
Jun 13, 2022
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In a study published in Science Advances magazine, researchers from the University of California, Irvine have captured, for the first time, the full-length structure of the rod photoreceptor phosphodiesterase 6 (PDE6), an ...
Apr 5, 2019
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Scientists at USC have discovered a new type of drug for the treatment of ovarian cancer that works in a way that should not only decrease the number of doses that patients need to take, but also may make it effective for ...
Oct 3, 2012
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The process researchers use to generate induced pluripotent stem cells (iPSCs)—a special type of stem cell that can be made in the lab from any type of adult cell—is time consuming and inefficient. To speed things up, ...
Sep 25, 2012
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In a mouse model of Alzheimer's disease, memory problems stem from an overactive enzyme that shuts off genes related to neuron communication, a new study says.
Feb 29, 2012
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A new research paper titled "IL-17 promotes IL-18 production via the MEK/ERK/miR-4492 axis in osteoarthritis synovial fibroblasts" has been published in Aging.
Feb 13, 2024
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Every day, people are exposed to a variety of synthetic chemicals through the products they use or the food they eat. For many of these chemicals, the health effects are unknown. Now a new study shows that several hundred ...
Jul 21, 2021
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