(Medical Xpress)—Analyzing genome-wide data from organisms, tissues or cells generates lists of genomic intervals – continuous structures on a genomic sequence, such as a chromosome. An interval's meaning is dependent ...
Japanese researchers identified chromosome aberrations as a new biomarker in predicting an esophageal cancer patient's risk of experiencing severe chemoradiotherapy side effects.
Oct 29, 2021
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Scientists have successfully sequenced the genome of a baby in the womb without tapping its protective fluid sac. This non-invasive approach to obtaining the fetal genome is reported in the June 6 issue of Science Translational ...
Jun 6, 2012
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A new research paper was published in Genes & Cancer on December 2, 2022, entitled, "Systems biology network reveals the correlation between COX-2 expression and Ch 7q copy number alterations in Ch 11q-deleted pediatric neuroblastoma ...
Dec 16, 2022
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An international team of researchers has now comprehensively profiled and categorized over 700 tumor samples from patients with chronic lymphocytic leukemia (CLL) by analyzing multiple levels of encoded biologic information.
Dec 6, 2021
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The process of in vitro fertilization (IVF) is often unsuccessful due to chromosomal changes that occur in an embryo fertilized in a test tube. So far, it was not known whether these changes also transfer to the baby, but ...
Nov 5, 2019
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Foetuses with a so-called new balanced chromosomal aberration have a higher risk of developing brain disorders such as autism and mental retardation than previously anticipated. The risk is 20 per cent for foetuses with these ...
May 25, 2018
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In a typical cancer cell, up to one-quarter of the genome is lost due to large chromosomal deletions, while the concomitant loss of hundreds of genes creates vulnerabilities that are impossible to reveal through the study ...
May 10, 2016
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Intratumor morphological heterogeneity (diversity) of breast cancer is not related to chromosome aberrations. This conclusion was made based on a study by researchers from Tomsk State University (TSU), Tomsk Cancer Research ...
Sep 30, 2015
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A genetic misfire called the 3q26.2 amplicon can cause real havoc. In fact, it is among the most frequent chromosomal aberrations seen in many cancers, including ovarian and breast cancers.
Dec 8, 2014
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