Inflammatory disorders

Cellular changes lead to chronic allergic inflammation in the sinus

Chronic rhinosinusitis is distinct from your average case of seasonal allergies. It causes the sinuses to become inflamed and swollen for months to years at a time, leading to difficulty breathing and other symptoms that ...


Budesonide with saline solution helpful for rhinosinusitis

(HealthDay)—The addition of budesonide to a saline nasal lavage for the treatment of chronic rhinosinusitis provides clinically meaningful benefits, according to a study published online June 7 in JAMA Otolaryngology-Head ...


Serum periostin IDs comorbid chronic rhinosinusitis in asthma

(HealthDay)—For patients with asthma, serum periostin is useful for detecting chronic rhinosinusitis with nasal polyps, according to a study published online March 1 in the Annals of the American Thoracic Society.


Verapamil benefits chronic rhinosinusitis with nasal polyps

(HealthDay)—For patients with chronic rhinosinusitis with nasal polyps (CRSwNP), the first-generation inhibitor of epithelial P-glycoprotein (P-gp; an efflux pump that is overexpressed in CRSwNP), verapamil hydrochloride ...

Diseases, Conditions, Syndromes

Recommended daily treatment for chronic rhinosinusitis underused

Topical intranasal steroid therapy continues to be underused for patients with chronic rhinosinusitis (CRS) despite practice guidelines that recommend daily use, according to a study published online by JAMA Otolaryngology-Head ...

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