Many types of cancer are caused by gene mutations in the signalling pathways that control cell growth, such as the hedgehog signalling pathway. A new study from the Karolinska Institutet, published in the journal Nature Communications, ...
Aug 8, 2016
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Scientists at the Gladstone Institutes have invented a new way to create three-dimensional human heart tissue from stem cells. The tissue can be used to model disease and test drugs, and it opens the door for a precision ...
Apr 20, 2016
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Researchers from the University of Liverpool working with colleagues from around the globe have found an explanation for how pancreatic cancer spreads to the liver. These findings potentially hold the key to stopping this ...
Apr 18, 2016
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Researchers have identified a molecular target and experimental treatment strategy for DNA repair defects behind Fanconi anemia - a complex genetic disorder responsible for birth anomalies, organ damage, anemia and cancer.
Jan 12, 2016
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(Medical Xpress)—A team of researchers from Harvard Medical School and Buck Institute for Research on Aging has conducted a study that has revealed that GATA4 (a transcription factor) plays a significant role in cell senescence. ...
Congenital diaphragmatic hernia (CDH) is not as well known as muscular dystrophy and cystic fibrosis, but like them it is a life-threatening birth defect, and is just as common. Occurring in one in 3,000 births, CDH causes ...
Mar 25, 2015
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Massachusetts General Hospital (MGH) researchers have used vascular precursor cells derived from human induced pluripotent stem cells (iPSCs) to generate, in an animal model, functional blood vessels that lasted as long as ...
Jul 15, 2013
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Repression of a single protein in ordinary fibroblasts is sufficient to directly convert the cells – abundantly found in connective tissues – into functional neurons. The findings, which could have far-reaching implications ...
Jan 10, 2013
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The stiffness of breast tissue is increasingly recognized as an important factor explaining the onset of breast cancer. Stiffening induces molecular changes that promote cancerous behavior in cells. Bioengineering studies ...
Sep 7, 2012
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(Medical Xpress) -- Discoveries by a Yale-led team of scientists could lead the way for development of new therapies for treating fibrosis and tumor metastasis. The researchers have both uncovered a signaling pathway that ...
May 21, 2012
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