Researchers at The Wistar Institute have found that combining PARP inhibitors, recently approved for the treatment of BRCA-mutant ovarian cancer, with another small molecule inhibitor was effective to treat ovarian cancers ...
Dec 19, 2017
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When you catch a nasty cold, curling up in bed to sleep may be the only activity you can manage. Sleeping in response to stress isn't a uniquely human behavior: many other animals have the same reaction, and it's not clear ...
Dec 15, 2017
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To understand what has gone wrong when cancer occurs and to create new possibilities for treatment, it is important to understand the molecular mechanisms behind what is happening at the cellular level. New research, which ...
Dec 7, 2017
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UT Southwestern Medical Center researchers have developed a method to map protein changes that occur in different subtypes of breast cancer cells in response to DNA damage from a new class of chemotherapy drugs.
Nov 29, 2017
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DNA damage occurs routinely within your cells due to sun exposure, smoking and sometimes during the normal process of making new DNA. Fortunately, there are "checkpoints" in-place within cells to stop them from making more ...
Oct 25, 2017
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Researchers at the University of Eastern Finland have discovered a novel mechanism safeguarding mitochondrial DNA. The study, published in PNAS earlier this week, was carried out in close collaboration with research groups ...
Oct 12, 2017
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Esophageal adenocarcinoma (EA) is an increasingly common cancer that silently affects the esophagus – the muscular tube that moves food into stomach. What causes EA is not well known but gastroesophageal reflux disease ...
Sep 15, 2017
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Liver cancer occurs predominantly in patients whose liver has been damaged as a result of chronic disease. Until now, it was not known how these events are linked at the molecular level. An international team of scientists ...
Sep 11, 2017
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Cancer is mostly caused by changes in the DNA of our cells that occur over a lifetime rather than inherited traits. Identifying the causes of these mutations is a difficult challenge because many processes can result in a ...
Jul 28, 2017
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Night shift work may hinder the body's ability to repair DNA damage caused by normal cellular processes, suggests a small study published online in Occupational & Environmental Medicine.
Jun 26, 2017
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