Cardiology
Single-cell sequencing takes a census in developing mouse hearts
It's not simple, making a heart.
Nov 16, 2016
0
1
Page 24 - News tagged with defective cells
Genetics
Researchers develop hematopoietic stem cell culture technology for safer and more effective genome editing
Hematopoietic stem cells (HSCs) are rare cells found in the bone marrow that produce red blood cells, white blood cells, and platelets. Their correct functioning is indispensable for the growth and health of an organism. ...
Jul 10, 2023
0
41
Medical research
Study finds novel gene correction model for epidermolysis bullosa
A research team led by pediatric blood and marrow transplantation experts Mark Osborn, Ph.D. and Jakub Tolar, M.D., Ph.D. from the Masonic Cancer Center, University of Minnesota, have discovered a remarkable new way to repair ...
Jun 6, 2013
0
0
Diseases, Conditions, Syndromes
New insight into RASopathy-associated lymphatic defects
The RAS pathway is a cellular signaling pathway that regulates growth and development in humans. RASopathies are a group of diseases characterized by defects in RAS signaling.
Feb 8, 2013
0
0
Cardiology
Regenerating damaged cardiac muscle
To mend a broken heart—that is, to regenerate a damaged cardiac muscle—it helps to know how hearts are built. "How does one stem cell, which has no specific identity, develop into multiple cell types that organize into ...
Aug 4, 2015
0
6
Genetics
Neurological disease in mice and humans linked to an unlikely gene
Screening for mutations influencing the migration of nerve cells in mice, scientists found a gene that plays a role in the transport of proteins within nerve cells. If less of the protein is present in the developing mouse, ...
Feb 1, 2018
0
1
Genetics
Testing the efficacy of new gene therapies more efficiently
Using a new cellular model, innovative gene therapy approaches for the hereditary immunodeficiency Chronic Granulomatous Disease can be tested faster and cost-effectively in the lab for their efficacy. A team of researchers ...
Mar 21, 2017
0
1
Genetics
Researchers pursue three gene therapies for rare inherited disease
When neurobiologist David Corey showed up at a rare disease conference in 2017, he had no idea that he would enter a race against time to develop a treatment for it.
Oct 19, 2023
0
0
Oncology & Cancer
Reprogrammed immune cells might give doctors an edge in rallying the body's defenses against tumor growth
Genetic abnormalities accrued by tumor cells lead to inappropriate production of proteins at the wrong time or place, or even the synthesis of unusual hybrid proteins not found in normal cells. Such abnormalities can serve ...
Mar 1, 2013
0
0
Medical research
Leaky lymphatics lead to obesity in mice
Lymphatic vessels play multifaceted roles in the body, including the absorption of dietary lipid in the intestines as well as the movement of immune cells throughout the body. Previous work by Guillermo Oliver and colleagues ...
Feb 25, 2016
0
1
