Scientists from the universities of Zurich and Duisburg-Essen have discovered a specific function of the protein p97/VCP. They demonstrate that the protein repairs DNA breaks like a corkscrew, a repair mechanism that could ...
Nov 8, 2011
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Scientists at the University of Bristol have discovered that a mechanism for preventing mutation within important genes involves long distance scanning of DNA by a molecular motor protein.
Feb 19, 2014
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Researchers have uncovered a novel pathway that explains how cancer cells become resistant to chemotherapies, which in turn offers a potential solution for preventing chemo-resistance.
Sep 20, 2022
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In a paper published in the May 13th, 2021 issue of PLOS Genetics, a Z-RNA nanoswitch that regulates interferon immune responses is described. The switch, less than 5 nanometer in length, is based on sequences, called flipons, ...
May 13, 2021
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Cancer treatment can rob childbearing-age women of fertility, but new research has uncloaked how the body's own traitor protein conspires with chemo and other harsh therapies against the ovaries' primordial follicles, home ...
Howard Hughes Medical Institute (HHMI) researchers have identified 27 genes in brain stem cells that are prone to a type of DNA damage. The fragility of those genes could explain why they are often mutated or deleted in cancers ...
Feb 11, 2016
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European scientists recently discovered a novel therapy to treat a subgroup of patients with hereditary breast/ovarian cancer. Both the EU and the US have approved an accelerated procedure to market this promising new treatment ...
Mar 20, 2015
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Our genetic material is constantly exposed to damage, which the body's own proteins normally repair. One of these proteins works like a scanner, continually scouring the genetic material for signs of damage. Researchers from ...
Jan 24, 2013
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A person doesn't have to go far to find a polycyclic aromatic hydrocarbon (PAH). These carcinogen precursors are inhaled through automobiles exhaust during the morning commute, are present in a drag of cigarette smoke, and ...
Nov 2, 2012
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We used to think that our fate was in the stars. Now we know in large measure, our fate is in our genes.
Apr 21, 2016
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