Genetics

Genome editing in mitochondria prevents inheritance of diseases

Mitochondrial diseases are maternally inherited genetic disorders that cause a wide spectrum of debilitating conditions and which currently have no cure. In a study published April 23 in the journal Cell, Salk Institute researchers ...

HIV & AIDS

Model explains why HIV prevention dosing differs by sex

A mathematical model developed by NIH grantees predicts that women must take the antiretroviral medication Truvada daily to prevent HIV infection via vaginal sex, whereas just two doses per week can protect men from HIV infection ...

Oncology & Cancer

DNA origami nano-tool provides important clue to cancer

Researchers at Karolinska Institutet have headed a study that provides new knowledge about the EphA2 receptor, which is significant in several forms of cancer. This is important knowledge in itself – but just as important ...

Genetics

Important discovery for the diagnosis of genetic diseases

A study conducted by Marie Kmita's team at the IRCM, in collaboration with Josée Dostie at McGill University, shows the importance of the chromatin architecture in controlling the activity of genes, especially those required ...

Medical research

New treatment for African sleeping sickness comes closer

Researchers at Umeå University have identified drugs targeting infections of the parasite Trypanosoma brucei and are thereby well on the way to find a cure against African sleeping sickness. This is the kernel of a thesis, ...

Neuroscience

RNA build-up linked to dementia and motor neuron disease

A new toxic entity associated with genetically inherited forms of dementia and motor neuron disease has been identified by scientists at the UCL Institute of Neurology. The toxin is the result of a genetic mutation that leads ...

Diseases, Conditions, Syndromes

Breakthrough model holds promise for treating Graves' disease

Researchers have developed the first animal model simulating the eye complications associated with the thyroid condition Graves' disease, a breakthrough that could pave the way for better treatments, according to a recent ...

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