New classes of therapeutic antisense oligonucleotides can have toxic effects on the liver. A novel machine learning-based approach used to predict the hepatotoxic potential of an antisense drug based on its chemical sequence ...
Aug 27, 2013
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(Medical Xpress)—Researchers in the U.S. have developed a new method to study damage to DNA and resultant translocations in living cells.
Researchers have designed tiny, light-controlled gold particles that can release DNA controls to switch blood clotting off and on. The results are reported July 24 in the open access journal PLoS ONE by Kimberly Hamad-Schifferli ...
Jul 24, 2013
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Herpes viruses are like tiny powder kegs waiting to explode. For more than 20 years scientists suspected that herpes viruses were packaged so full of genetic material that they built up an internal pressure so strong it could ...
Jul 24, 2013
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New data on an emerging treatment that aims to fight colorectal cancer by stimulating the immune system have been presented at the ESMO 15th World Congress on Gastrointestinal Cancer.
Jul 3, 2013
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When DNA that turns up in the wrong place in mammalian cells, the innate immune system reacts by secreting interferons. The structure and mode of action of the enzyme that mediates this response have now been elucidated.
Jun 4, 2013
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A change to the so-called TERT gene considerably increases the risk of breast and ovarian cancer. This is the result of a current, multicenter study in which the University Department of Gynaecology and the Comprehensive ...
May 10, 2013
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Scientists at the University of Essex have made a further step towards the potential future development of medicines to help combat a range of diseases currently considered "undruggable".
Apr 30, 2013
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(Medical Xpress)—Researchers at the University of Illinois have identified biomarkers that can be used to determine ovarian cancer survival and recurrence, and have shown how these biomarkers interact with each other to ...
Apr 30, 2013
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A Big Data analysis that integrates three large sets of genomic data available through The Cancer Genome Atlas has identified 37 RNA molecules that might predict survival in patients with the most common form of breast cancer.
Apr 29, 2013
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