Scientists uncover DNA 'shield' with crucial roles in normal cell division
Scientists have made a major discovery about how cells repair broken strands of DNA that could have huge implications for the treatment of cancer.
Jul 18, 2018
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Scientists have made a major discovery about how cells repair broken strands of DNA that could have huge implications for the treatment of cancer.
Jul 18, 2018
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Fanconi anemia (FA) is caused by defective genes for DNA-repair leading to bone marrow failure, developmental abnormalities and increased cancer risk. Using genome-wide genetic approaches, researchers at CeMM systematically ...
Jun 12, 2018
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The findings revealed that a special group of genes that function within the body's normal DNA repair process were vital to the effectiveness of p53. This new information could help doctors to better identify patients with ...
Jun 11, 2018
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Mutations in genes that help repair damage to DNA may aid in predicting the prognosis of patients with bladder and other related cancers, according to researchers.
May 15, 2018
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Mutations driving cancer development leave behind specific 'scars," so-called mutational signatures, in the genome. In principle, they allow for profiling of the cancer type and its development—but the noisy environment ...
May 9, 2018
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Penn Medicine researchers have used CRISPR/Cas9 gene editing technology to isolate a key genetic feature that could cause resistance to PARP inhibitors in patients with ovarian cancer—and they've also proven they have a ...
Apr 26, 2018
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Results from an important NASA experiment – in which astronaut Scott Kelly spent one year in space while his identical twin brother Mark stayed on Earth – have started to come in. Last week, a number of media outlets ...
Mar 22, 2018
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An international team of researchers found how cancer cells respond to DNA damage signaling when in low oxygen, or hypoxia. Through comprehensive gene expression analyses, the team determined how one family of genes controls ...
Mar 20, 2018
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An analysis of nearly 3,800 colorectal cancer patients—the largest germline risk study for this cancer to date—reveals opportunities for improved risk screening and, possibly, treatment.
Feb 23, 2018
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Researchers at the University of Oxford have discovered that a cellular mechanism preferentially protects plant genes from the damaging effects of mutation.
Jan 5, 2018
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