Pediatrics

Using big data to save babies

Although bronchopulmonary dysplasia (BPD)—a chronic lung disease affecting newborns—is the most common complication of preterm birth, it remains difficult to diagnose and treat. Researchers from Fundación INFANT in Buenos ...

Health

Clues to lung injury in preterm babies

Bronchopulmonary dysplasia (BPD)—a form of chronic lung disease—is a leading complication of preterm birth affecting infants born before 32 weeks gestation. Exposure to high levels of oxygen (hyperoxia) plays a role in ...

Pediatrics

High-dose erythropoietin no benefit for extreme preemies

(HealthDay)—For extremely preterm infants, high-dose erythropoietin treatment from 24 hours after birth does not result in a reduced risk for severe neurodevelopmental impairment or death at age 2 years, according to a ...

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Dysplasia

Dysplasia (from the Greek δυσπλασία "malformation", δυσ- "mal-" + πλάθω "to create, to form"), is a term used in pathology to refer to an abnormality of development. This generally consists of an expansion of immature cells, with a corresponding decrease in the number and location of mature cells. Dysplasia is often indicative of an early neoplastic process. The term dysplasia is typically used when the cellular abnormality is restricted to the originating tissue, as in the case of an early, in-situ neoplasm.

Dysplasia, in which cell maturation and differentiation are delayed, can be contrasted with metaplasia, in which cells of one mature, differentiated type are replaced by cells of another mature, differentiated type.

The terms hip dysplasia and fibrous dysplasia also refer to abnormal development, but at a more macroscopic level.

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