Most neurodegenerative diseases, including dementias, involve proteins aggregating into filaments called amyloids. In most of these diseases, researchers have identified the proteins that aggregate, allowing them to target ...
Dec 6, 2023
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The human immunodeficiency virus (HIV) is a formidable pathogen. It mutates rapidly; in fact, estimates suggest that the genetic diversity of HIV in a single person at one point in time is equal to the diversity of influenza ...
Nov 22, 2023
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Neurons talk to each other using chemical signals called neurotransmitters. Scientists at St. Jude Children's Research Hospital have drawn on structural biology expertise to determine structures of vesicular monoamine transporter ...
Nov 1, 2023
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An early phase in the process of developing Alzheimer's disease is a metabolic increase in a part of the brain called the hippocampus, report researchers from Karolinska Institutet in a study published in Molecular Psychiatry. ...
Oct 31, 2023
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Researchers at Nagoya University in Japan have created and improved artificial intelligence (AI) designs to synthesize a candidate compound for a new gastric acid inhibitor with a better binding affinity than existing drugs. ...
Oct 27, 2023
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In the intricate dance of our body's defenses against harmful invaders, certain immune system proteins play pivotal roles. New research from the Bridge Institute at the USC Michelson Center for Convergent Bioscience, in collaboration ...
Oct 17, 2023
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Researchers have now combined STED microscopy, a technology that allows superresolution visualization, and a recently created new antibody to observe the amyloidogenic aggregates characteristic of Alzheimer's disease. The ...
Oct 11, 2023
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A new study spearheaded by the University of Ottawa's Faculty of Medicine lab has unveiled a previously unrecognized role for an essential nutrient in shaping the cellular landscape for one of the body's first lines of defense ...
Oct 5, 2023
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Parkinson's disease is a complex neurodegenerative disorder that leads to the deterioration of specific types of neurons in the brain, resulting in a number of motor and non-motor symptoms. It is currently estimated that ...
Sep 28, 2023
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Many neurodegenerative diseases, including Alzheimer's, are characterized by tangled proteins called Tau fibrils. In a new study, MIT chemists have gained insight into how these fibrils form and identified a potential target ...
Jul 17, 2023
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