Medical research

Solving the CNL6 mystery in Batten disease

Batten disease is a family of 13 rare, genetically distinct conditions. Collectively, they are the most prevalent cause of neurodegenerative disease in children, affecting 1 in 12,500 live births in the U.S. One of the Batten ...

Dentistry

Study reveals how too much fluoride causes defects in tooth enamel

Exposing teeth to excessive fluoride alters calcium signaling, mitochondrial function, and gene expression in the cells forming tooth enamel—a novel explanation for how dental fluorosis, a condition caused by overexposure ...

Neuroscience

The ever-changing brain: Shining a light on synaptic plasticity

Synapses allow neurons to communicate with one another. In the synapse, one neuron emits chemical messengers called neurotransmitters, and an adjacent neuron receives them using tiny structures called receptors. A specific ...

Neuroscience

Rotavirus cell invasion triggers a cacophony of calcium signals

To successfully set off disease, rotavirus, a virus that causes severe diarrhea and vomiting in children around the world, must invade cells of the gastrointestinal track and trigger a surge of calcium inside the cells. How ...

Medical research

Scientists delineate pathway that helps us make antibodies

Our bodies are continuously concocting specific antibodies to thwart invaders like a virus or even pollen, and scientists have new information about how the essential production gets fired up and keeps up.

Medical research

Nicotine works inside cells to reinforce addiction: study

When a person takes a puff on a cigarette, nicotine floods into the brain, latching onto receptors on the surface of neurons and producing feelings of happiness. But nicotine does not simply stay on the surface of cells—the ...

Immunology

Stress related responses regulate immune function

The immune system is composed of a wide range of different immune cells each with dedicated functions. Natural killer T cells form a specialized immune cell that protects against a variety of diseases such as cancer, autoimmunity, ...

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