Oncology & Cancer

Initiation, adherence to AIs low for older women with DCIS

(HealthDay)—For older women with estrogen receptor (ER)-positive ductal carcinoma in situ (DCIS), initiation of aromatase inhibitors (AIs) and adherence to treatment are low, according to a study published online Oct. 25 ...

Oncology & Cancer

Estrogen signaling impacted immune response in cancer

While the role of estrogen signaling in tumor development is well understood in breast and ovarian cancer, its role in anti-tumor immunity has not been extensively studied. However, new research from The Wistar Institute ...

Oncology & Cancer

Tamoxifen resistance linked to high estrogen levels in utero

An animal study suggests that resistance to tamoxifen therapy in some estrogen receptor positive breast cancers may originate from in utero exposure to endocrine disrupting chemicals. The study provides a new path forward ...

Oncology & Cancer

Cross talk between hormone receptors has unexpected effects

One of the first clues pathologists look for in tissue from a newly diagnosed breast cancer patient is the estrogen receptor, a nuclear protein that converts hormonal messages in the bloodstream into instructions for the ...

Oncology & Cancer

Extended elevated recurrence rates for ER-positive breast CA

(HealthDay)—Breast cancer patients with estrogen receptor (ER)-positive disease have elevated annualized hazards of recurrence during extended follow-up, according to a study published online Jan. 18 in the Journal of Clinical ...

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