Breast cancer (BC) remains one of the most challenging cancers to treat, primarily due to its heterogeneity and propensity for metastasis. The Notch signaling pathway is integral to various cellular processes and has been ...
Jul 23, 2024
0
0
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive form of leukemia that arises from the malignant transformation of T-cell progenitors. This disease is most commonly diagnosed in children, where it accounts for ...
Jul 23, 2024
0
0
The Association for Molecular Pathology (AMP) has published consensus recommendations to aid in the design and validation of clinical DPYD genotyping assays, promote standardization of testing across different laboratories, ...
Jul 22, 2024
0
0
The human epidermal growth factor receptor 2 (HER2) is a critical protein in the growth of cancer cells, and its expression level is a vital indicator of breast cancer aggressiveness. Traditionally, HER2 status is assessed ...
Jul 17, 2024
0
0
Most research in human genetics has historically focused on people of European ancestries—a long-standing bias that may limit the accuracy of scientific predictions for people from other populations.
Jul 17, 2024
0
30
Chronic pain affects approximately 20% of the United States population and 30% of the global population. Along with sensory manifestations, chronic pain conditions also are associated with high rates of comorbid depression ...
Jul 11, 2024
0
1
Mass Eye and Ear researchers restored hearing in preclinical mouse models with a specific form of inherited deafness called DFNA50 caused by mutations in microRNA, by using a novel in vivo CRISPR genome editing approach. ...
Jul 11, 2024
0
32
One of the hallmarks of aging is difficulty getting to sleep and staying asleep. On average, younger adults may wake up briefly five times a night. But some people over age 60 may wake up as many as 150 times while sleeping.
Jul 10, 2024
0
1
Despite recent advancements in the treatment of Parkinson's disease, it remains a challenge to accurately measure the progression of symptoms in this neurological disorder. While noticeable symptoms like tremors, stiffness ...
Jul 9, 2024
0
23
A class of proteins that regulates cell repair and enhances cell growth-signaling systems could be a promising new target for the treatment of Alzheimer's and other neurodegenerative diseases, according to a new study led ...
Jul 2, 2024
0
41
