It's the most common cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), but until now scientists weren't sure how a specific gene caused these devastating diseases. Now researchers from the University ...
Oct 5, 2015
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A spectrum of neurodegenerative diseases, including frontotemporal dementia (FTD), progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) are due to the accumulation of abnormal, misfolded tau proteins in ...
Apr 4, 2024
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An international team of researchers identified a pathogenic mechanism that is common to several neurodegenerative diseases. The findings suggest that it may be possible to slow the progression of dementia even after the ...
Jul 3, 2014
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Limbic predominate age-related TDP-43 encephalopathy or LATE is a recently recognized form of dementia that affects memory, thinking and social skills. It mimics Alzheimer's disease or AD (and sometimes co-exists with it), ...
Dec 15, 2022
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Inhibition of the PREP enzyme was successful in stopping the progression of frontotemporal dementia in a mouse model of the disease, according to a new study published in Science Translational Medicine. PREP inhibitor treatment ...
Apr 13, 2023
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IBMPFD is a rare and deadly genetic disorder that has devastated entire families, robbing many of their members of their ability to talk, walk and think clearly.
Mar 16, 2015
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ALS—amyotrophic lateral sclerosis—is a neurodegenerative disease that attacks motor neurons in the brain and spinal cord, slowly robbing its victims of their ability to walk, talk, breathe and swallow. In a cruel twist, ...
Aug 20, 2018
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The ALS-related protein TDP-43 takes the first steps toward pathologic aggregation as part of its normal function, according to a new study publishing in the Open Access journal PLOS Biology on Jan. 6, 2016. The study, by ...
Jan 6, 2016
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Nagoya University-led research identifies role for neuronal protein interaction in preventing frontotemporal lobar degeneration, a dementia that starts in middle age.
Feb 13, 2017
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A new diagnostic tool helps clinicians to differentiate between Alzheimer's disease, frontotemporal dementia and mild cognitive impairment. Presented in the doctoral thesis of MD Miguel Ángel Muñoz Ruiz at the University ...
Jun 5, 2014
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