Oncology & Cancer

Researchers reveal mechanism of drug reactivating tumor suppressors

Researchers have revealed the mechanism of a drug shown to be effective in treating certain types of cancer, which targets a protein modification silencing the expression of multiple tumor suppressor genes. They also demonstrated ...

Genetics

Researchers uncover molecular pathways underlying depression

Depression is a common mental health problem that affects people across demographics. Scientists have long known that there may be a genetic component that confers predisposition to depression, but the specific underlying ...

Oncology & Cancer

Impact of epigenetics on the clinical management of cancer patients

In the early 1980s, the first changes in DNA related to a chemical modification called methylation were discovered, followed by the discovery in the mid-1990s of the first tumor suppressor genes inactivated by these modifications ...

Psychology & Psychiatry

A new way to treat PTSD?

Exposure to a traumatic experience can lead to post-traumatic stress disorder (PTSD), an incapacitating disorder in susceptible persons with no reliable therapy. Particularly puzzling is understanding how transient exposure ...

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