Diseases, Conditions, Syndromes

RNA modification may protect against liver disease

A chemical modification that occurs in some RNA molecules as they carry genetic instructions from DNA to cells' protein-making machinery may offer protection against non-alcoholic fatty liver, a condition that results from ...

Medical research

How cells keep gene silencing in check

Long considered 'junk," non-coding RNAs have emerged as important regulators of diverse cellular processes, including the silencing of genes. Working in yeast, researchers from the Bühler group have identified more than ...

Health

No level of smoke exposure is safe during pregnancy

Nearly a quarter of pregnant women say they've been around secondhand smoke—in their homes, at work, around a friend or relative—which, according to new research, is linked to epigenetic changes—meaning changes to how ...

Medical research

New drug combination shows promise as powerful treatment for AML

Scientists have identified two drugs that are potent against acute myeloid leukemia (AML) when combined, but only weakly effective when used alone. The researchers were able to significantly enhance cancer cell death by jointly ...

Oncology & Cancer

Scientists uncover signposts in DNA for cancer, disease risk

By sequencing entire genomes for DNA modifications, and analyzing both cancer tissues and healthy ones, Hackensack Meridian Health researchers and doctors have found what could be a key to risks for cancer and other diseases: ...

Medical research

A new genetic tool to modify and understand gene function

Scientists of the National Center for Cardiovascular Research (CNIC) led by Rui Benedito have developed a new genetic tool called iSuRe-Cre that provides certainty in Cre-inducible genetic modifications, a key technique for ...

Psychology & Psychiatry

Epigenetics contribute to male and female differences in fear memory

In a mouse model of traumatic memory, male mice recall fear-related memories better than female mice, according to a study in Biological Psychiatry. The difference between sexes was attributed to a gene important for creating ...

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