Medical research

Alternative splicing is crucial to muscle mass maintenance

Despite the importance that changes in muscle mass have in aging, overall body metabolism and in chronic disease, we still don't fully understand the mechanisms that contribute to the maintenance of adult muscle mass.

Medical research

Change in protein production essential to muscle function

Researchers at Baylor College of Medicine have shed light on the process that guides the maturation of newborn muscles into adult, fully functional organs. In mice, they determined that a group of genes involved in calcium ...

Parkinson's & Movement disorders

New study surveys genetic changes linked with Parkinson's disease

After Alzheimer's, Parkinson's disease (PD) is the leading neurodegenerative disorder, affecting close to a million Americans, with 50,000 new cases diagnosed every year. A progressive disorder of the nervous system affecting ...

Genetics

Yin and yang in retinal degeneration

Mutations in the peripherin-2 gene are among the major causes of retinal degeneration. LMU researchers have now discovered why different mutations in the gene preferentially affect one or other of the two types of photoreceptor ...

Genetics

How mutations in a high risk gene affect motor neurons

Scientists at the flagship motor neuron disease research centre, based at the University of Sheffield, investigated how specialised nerve cells that control voluntary movements die – something which is key to understanding ...

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