Genetics has made huge strides over the past 20 years, from the sequencing of the human genome to a growing understanding of factors that turn genes on and off, namely transcription factors and the DNA "enhancer" sequences ...
Dec 22, 2020
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Researchers have provided new insight on the role of cyclic AMP (cAMP) in regulating the immune response.
Feb 4, 2020
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Garbage comes in all shapes and sizes. Cells, the body's functional units of life, also produce 'garbage' - debris and dysfunctional elements the body must get rid of. Failure to dispose of this garbage could trigger various ...
Jun 24, 2011
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Many cancer cells never leave their original tumors. Some cancer cells evolve the ability to migrate to other tissues, but once there cannot manage to form new tumors, and so remain dormant. The deadliest cancer cells are ...
Jan 5, 2023
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In the current issue of Proceedings of the National Academy of Sciences, researchers from Nationwide Children's Hospital describe a new paradigm for treating transcription factor-driven cancers. The study focuses on Ewing ...
Sep 18, 2017
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Unlike most T cells, which launch immune responses against foreign molecules, regulatory T cells are the peacekeepers of the human immune system, damping down inflammatory reactions when they're not needed. Now, researchers ...
Oct 1, 2020
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There are roughly 20,000 genes and thousands of other regulatory "elements" stored within the three billion letters of the human genome. Genes encode information that is used to create proteins, while other genomic elements ...
Nov 10, 2014
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Immune system T cells that should be able to kill cancer cells become dysfunctional or "exhausted" within hours of encountering a tumor, according to a study reported Aug. 3 in Nature Immunology.
Aug 3, 2023
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The process of cell division is tightly regulated, as mistakes may lead to cancer. The so-called c-JUN protein has been fingered as causing tumors in both skin and liver. The group of Veronika Sexl at the University of Veterinary ...
Jun 28, 2011
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Proteins that are frequently altered in tumors play a prominent role in cancer research. The protein RFX7, a largely unknown transcription factor, has recently been linked to lymph node cancer. Researchers at the Leibniz ...
Jul 19, 2022
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