Proteins that are frequently altered in tumors play a prominent role in cancer research. The protein RFX7, a largely unknown transcription factor, has recently been linked to lymph node cancer. Researchers at the Leibniz ...
Jul 19, 2022
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(HealthDay) -- Chrysotile, a commercially used type of asbestos, induces malignant mesothelioma (MM) in the rat peritoneal cavity, with pathogenesis strongly linked to iron overload, according to a study published online ...
Aug 14, 2012
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Our bodies make blood in a specialized niche—a "nursery" within our bone marrow that nurtures blood stem cells so they can replicate and make different kinds of blood cells. The lab of Leonard Zon, MD, has even shown how ...
May 24, 2023
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A gene long presumed dead comes to life under the full moon of inflammation, Stanford University School of Medicine scientists have found.
Jul 23, 2013
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How do cis-regulatory genome elements regulate gene expression, what are the critical components involved, and can we therapeutically target them? By investigating how corepressors modulate enhancers and silencers during ...
Jan 27, 2021
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In research published in Nature Structural & Molecular Biology, researchers from the University of Birmingham have found that transcription start sites (TSS) have a significant role in determining cancer cell behavior.
Nov 24, 2023
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(Medical Xpress)—Researchers at the University of Illinois have identified biomarkers that can be used to determine ovarian cancer survival and recurrence, and have shown how these biomarkers interact with each other to ...
Apr 30, 2013
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A form of blood cancer known as mantle cell lymphoma is critically dependent on a protein that coordinates gene expression, such that blocking its activity with an experimental drug dramatically slows the growth of this lymphoma ...
Nov 22, 2022
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Over two million babies, children, and adults in the United States are living with congenital heart disease—a range of birth defects affecting the heart's structure or function. Now, researchers at Gladstone Institutes ...
Dec 14, 2020
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Inside embryonic cells, specific proteins control the rate at which genetic information is transcribed from DNA to messenger RNA—a crucial regulatory step before proteins are created. Then, organs develop and hopefully ...
Apr 27, 2022
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