Genetics
'Junk DNA' is a double-edged sword, and the good side has anti-cancer potential
Rochester biologists show how selfish genetic elements that can cause tumors may also trigger the death of cancer cells.
Oct 21, 2021
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News tagged with genetic element
Genetics
Humans may have benefited from mobile genetic element insertions
Mobile pieces of DNA can jump around in the human genome and exert powerful regulatory effects on neighboring genes at new insertion sites. The most common mobile genetic elements are known as LINE-1 retrotransposons and ...
Sep 10, 2014
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Genetics
First 'non-gene' mutations behind neurodevelopmental disorders discovered
In the largest study of its kind, genetic changes causing neurodevelopmental disorders have been discovered by scientists at the Wellcome Sanger Institute and their collaborators in the NHS Regional Genetics services. The ...
Mar 21, 2018
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Genetics
New approach to link genome-wide association signals to biological function
Researchers have developed a new strategy to improve the outcome of genome-wide association (GWA) studies.
Jun 30, 2011
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Genetics
Find-and-replace genome editing with CRISPR: A promising therapeutic strategy
Severe combined immunodeficiencies (SCIDs) are a group of debilitating primary immunodeficiency disorders, primarily caused by genetic mutations that disrupt T-cell development. SCID can also affect B-cell and natural killer ...
Oct 27, 2023
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Genetics
About face: Long-ignored segments of DNA play role in early stages of face development
(Medical Xpress)—The human face is a fantastically intricate thing. The billions of people on the planet have faces that are individually recognizable because each has subtle differences in its folds and curves. How is ...
Oct 22, 2012
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Oncology & Cancer
New research sheds light on the molecular mechanisms by which a virus contributes to cancer
Hepatocellular carcinoma (HCC) is the third leading cause of cancer deaths worldwide and is associated with exposure to hepatitis B virus (HBV). Patients carrying the virus have a 100-fold greater risk of developing HCC, ...
Aug 29, 2012
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Genetics
Screening the dark genome for disease
Researchers have developed a method to swiftly screen the non-coding DNA of the human genome for links to diseases that are driven by changes in gene regulation. The technique could revolutionize modern medicine's understanding ...
Apr 3, 2017
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Genetics
A stem cell model could help unravel the complex biology behind some psychiatric disorders
Researchers from the Icahn School of Medicine at Mount Sinai have applied a novel stem cell model to map disease risk variants in human neurons, which could help provide insights into the biological mechanisms that underlie ...
Jun 1, 2022
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Diseases, Conditions, Syndromes
Acid reflux? It's in the genes
(Medical Xpress)—For many years it has been thought that acid reflux and a related condition called Barrett's Oesophagus were acquired conditions, via diet, smoking and other lifestyle activities. However, recent family ...
Apr 3, 2013
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