Mobile pieces of DNA can jump around in the human genome and exert powerful regulatory effects on neighboring genes at new insertion sites. The most common mobile genetic elements are known as LINE-1 retrotransposons and ...
Sep 10, 2014
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In the largest study of its kind, genetic changes causing neurodevelopmental disorders have been discovered by scientists at the Wellcome Sanger Institute and their collaborators in the NHS Regional Genetics services. The ...
Mar 21, 2018
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Rochester biologists show how selfish genetic elements that can cause tumors may also trigger the death of cancer cells.
Oct 21, 2021
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Severe combined immunodeficiencies (SCIDs) are a group of debilitating primary immunodeficiency disorders, primarily caused by genetic mutations that disrupt T-cell development. SCID can also affect B-cell and natural killer ...
Oct 27, 2023
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Researchers have developed a new strategy to improve the outcome of genome-wide association (GWA) studies.
Jun 30, 2011
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(Medical Xpress)—The human face is a fantastically intricate thing. The billions of people on the planet have faces that are individually recognizable because each has subtle differences in its folds and curves. How is ...
Oct 22, 2012
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A team led by researchers at UT Southwestern Medical Center has developed deep learning models to identify a simple set of rules that govern the activity of promoters—regions of DNA that initiate the process by which genes ...
May 14, 2024
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Hepatocellular carcinoma (HCC) is the third leading cause of cancer deaths worldwide and is associated with exposure to hepatitis B virus (HBV). Patients carrying the virus have a 100-fold greater risk of developing HCC, ...
Aug 29, 2012
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Researchers have developed a method to swiftly screen the non-coding DNA of the human genome for links to diseases that are driven by changes in gene regulation. The technique could revolutionize modern medicine's understanding ...
Apr 3, 2017
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Researchers from the Icahn School of Medicine at Mount Sinai have applied a novel stem cell model to map disease risk variants in human neurons, which could help provide insights into the biological mechanisms that underlie ...
Jun 1, 2022
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