Researchers at the National University in Singapore and colleagues in the US and China undertook a two-decade metabolic analysis of Global Burden of Disease (GBD) reports. They have published their findings in the journal ...
Chronic kidney disease (CKD) is a feature of inherited metabolic disorders such as methylmalonic acidimia (MMA), which can cause impaired growth and low metabolic activity to delay the diagnosis and management of renal disease. ...
A small chemical change—shifting the position of two hydrogen atoms—makes the difference between mice that are healthy and mice with insulin resistance and fatty liver, major risk factors for diabetes and heart disease. ...
Jul 4, 2019
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Researchers at Karolinska Institutet may have found a new way to treat obesity and related disorders by targeting the cells' mitochondria. A study published in Nature Metabolism shows that a specific class of drugs that block ...
Apr 30, 2024
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New research from the University of Aberdeen could lead to the development of medication for disease that affects 1 in 4 people worldwide but is currently untreatable.
Apr 30, 2024
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A South Korean team has spearheaded a research endeavor that successfully uncovered the mechanisms governing inflammation and metabolic dysfunction in tissues associated with obesity. Their findings were published in Nature ...
Apr 25, 2024
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Researchers at Karolinska Institutet have developed a method to study liver function and disease without requiring invasive procedures. After transplanting liver cells into the eye of mice, the cornea can be used as a window ...
Feb 1, 2024
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Old, obese flies get healthier and live longer if put on a diet, University of Connecticut researchers report on Dec. 8 in PNAS. If the effect holds true for humans, it would mean it's never too late for obese people to improve ...
Dec 12, 2023
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Gene therapy has great promise for treating genetic diseases, and even for more common diseases such as atherosclerosis (hardening of the arteries). Over the past decade, the gene-editing technology CRISPR (Clustered Regularly ...
Nov 16, 2023
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Scientists from Duke-NUS Medical School, in collaboration with counterparts from Columbia University, have developed a new framework to measure metabolic health. The concept of "metabolic elasticity" paints a more comprehensive ...
Nov 2, 2023
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