The Hippo pathway is an important biological tumor suppressor program that controls cell growth and organ size in humans. Cancer cells have been found to frequently deactivate Hippo signaling in order to achieve increased ...
Apr 4, 2019
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It's known that cancer involves unchecked cell growth and that a biological pathway that regulates organ size, known at the Hippo pathway, is also involved in cancer. It's further known that a major player in this pathway, ...
Nov 20, 2018
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Like detectives tracking a serial killer, St. Jude Children's Research Hospital scientists have identified a novel mechanism that may help promote the growth and spread of solid tumors. The findings appeared online Oct. 25 ...
Oct 31, 2018
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UT Southwestern researchers have made a major advance in uncovering the biology of how thousands of disfiguring skin tumors occur in patients troubled by a genetic disorder called neurofibromatosis type 1 (NF1). This scientific ...
Oct 23, 2018
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With an estimated twenty-thousand protein-coding genes in the human genome, pinpointing a specific gene or pathway responsible for a particular disease can be like finding a needle in the proverbial haystack. This has certainly ...
Oct 17, 2018
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University of Toronto researchers have uncovered why some cancers grow faster than others. The team led by Liliana Attisano, Professor in U of T's Donnelly Centre for Cellular and Biomolecular Research, has identified a protein ...
Aug 29, 2018
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Using a technology that provides a 'high-resolution view' of the status of individual cells, a team of researchers has gained new insights into the embryonic development of the mouse heart. They discovered that during development, ...
Apr 23, 2018
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Researchers have discovered a previously unrecognized healing capacity of the heart. In a mouse model, they were able to reverse severe heart failure by silencing the activity of Hippo, a signaling pathway that can prevent ...
Oct 4, 2017
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Heart muscle is one of the least renewable tissues in the body, which is one of the reasons that heart disease is the leading cause of death for both men and women in the United States, according to the Centers for Disease ...
Jun 5, 2017
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There is an old axiom among cell biologists meant to caution against making assumptions about how certain proteins function, and it involves a hypothetical Martian. If that Martian came to Earth and looked down at a school ...
Mar 13, 2017
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