Circadian rhythms can influence drugs' effectiveness
Giving drugs at different times of day could significantly affect how they are metabolized in the liver, according to a new study from MIT.
Apr 24, 2024
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Giving drugs at different times of day could significantly affect how they are metabolized in the liver, according to a new study from MIT.
Apr 24, 2024
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In a worldwide first-of-its-kind study published in the journal Nature Communications this week, a team of scientists from Children's Medical Research Institute (CMRI) have tested novel gene therapies in a whole human liver, ...
Mar 14, 2024
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The gut microbiome interacts with the loss of female sex hormones to exacerbate metabolic disease, including weight gain, fat in the liver and the expression of genes linked with inflammation, researchers found in a new rodent ...
Feb 22, 2024
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When asked about what could cause cancer, people most likely think of chemicals like tobacco or radiation such as UV light in sunshine, but chronic jet lag probably does not come to mind. Human epidemiological studies have ...
Feb 7, 2024
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A joint research team has used stem cells to generate human immune cells for application in cancer immunotherapy. By replicating the natural process through which our bodies generate immune cells, this breakthrough platform ...
Feb 6, 2024
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Metabolic dysfunction-associated steatohepatitis, or MASH, is an inflammatory, liver-scarring disease that has reached epidemic proportions, with an estimated 1.5% to 6.5% of U.S. adults afflicted by the condition, and roughly ...
Jan 23, 2024
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During oxidative stress, excess production of reactive oxygen species causes cell and tissue damage.
Dec 21, 2023
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In a new study, researchers at the University of Chicago were able to predict postoperative infections in liver transplant patients by analyzing molecules in their poop. Their analysis represents a key leap forward in exploring ...
Dec 16, 2023
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A study, published in the journal Gene Expression and led by Brady Jin-Smith from the Department of Pathology at Tulane University, focuses on ALDHs, a group of key enzymes that catalyze the irreversible oxidation of various ...
Dec 15, 2023
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Non-alcoholic fatty liver disease (NAFLD) is a major health problem affecting approximately 30% of people in Western countries and which has been in sharp increase over the last three decades.
Dec 5, 2023
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