Researchers at Massachusetts General Hospital (MGH) have identified a potential mechanism by which tobacco smoking drives a type of white blood cell known as monocytes to the lung where they can increase the risk of active ...
Dec 13, 2023
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Drug development for lung diseases is complicated. Most clinical trials that test novel drugs fail due to the fact that laboratory models cannot accurately replicate human physiology.
Dec 6, 2023
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Another at-home treatment option for the flu and other respiratory illnesses is closer to becoming a reality, thanks to new research that found inhaled, monoclonal antibodies against SARS-CoV-2 significantly reduced COVID-19 ...
Nov 7, 2023
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Cancer cells are often a mess of mutations. About 20% to 25% of cancers involve mutations in a complex of molecules called SWI/SNF. Yet drugs designed to block SWI/SNF activity haven't always worked as expected. Researchers ...
Nov 3, 2023
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After birth, the human heart loses its regenerative capacity almost completely. Damage to the heart muscle—for example, due to a heart attack—therefore usually leads to a permanent loss of function in adults. Scientists ...
Oct 24, 2023
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Lung cancer cells that metastasize to the brain survive by convincing brain cells called astrocytes that they are baby neurons in need of protection, according to a study by researchers at Stanford Medicine.
Oct 24, 2023
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The lung is one of the tissues most sensitive to radiation in the human body. People exposed to high radiation doses following nuclear incidents develop radiation-induced lung injury (RILI), which affects the function of ...
Oct 17, 2023
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University of Toronto (U of T) researchers have found that cancer cells can enhance tumor growth by hijacking enhancer DNA normally used when tissues and organs are formed. The mechanism, called enhancer reprogramming, occurs ...
Sep 29, 2023
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Researchers at Rutgers Cancer Institute of New Jersey and Rutgers New Jersey Medical School (NJMS), together with other collaborating groups, have discovered the first lipid vascular "ZIP code" in the lungs. Getting a drug ...
Aug 14, 2023
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A mammalian protein previously shown by UT Southwestern microbiologists to inhibit the virus that causes COVID-19 in cell culture also protected live mouse models, significantly limiting infection in the lung cells and diminishing ...
Jul 31, 2023
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