Weizmann Institute scientists have discovered two small molecules that can cross the blood-brain barrier in mice, slowing and even reversing the effects of Huntington's, which is incurable.
Feb 26, 2024
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A team with the participation of researchers from the Institute for Advanced Chemistry of Catalonia (IQAC) of the Spanish National Research Council (CSIC) has revealed the structure of the protein responsible for Huntington's ...
Apr 20, 2023
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Investigators led by D. James Surmeier, Ph.D., the Nathan Smith Davis Professor and chair of Neuroscience, have uncovered previously unknown neuronal circuits that contribute to brain dysfunction in Huntington's disease.
Apr 17, 2023
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Huntington's disease is a progressively debilitating brain disease that causes uncontrolled movements, psychological problems, and loss of cognition. Huntington's is caused by a mutation in the gene that encodes huntingtin, ...
Nov 12, 2021
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Huntington's disease is a genetic neurodegenerative disorder caused by mutations in the protein huntingtin and characterized by involuntary dance-like movements, severe behavioral changes and cognitive impairment. That neuronal ...
Apr 13, 2021
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A Duke University research team has identified a new function of a gene called huntingtin, a mutation of which underlies the progressive neurodegenerative disorder known as Huntington's Disease.
Jan 21, 2020
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An MDC research team reports in the journal Molecular Cell that short protein fibers precede the formation of larger deposits that accumulate in the brains of those affected by the incurable Huntington's disease, sometimes ...
Sep 6, 2018
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A new study published in the Proceedings of the National Academy of Sciences (PNAS) suggests that Huntington's disease may take effect much earlier in life than was previously believed, and that a new drug may be key in controlling ...
Sep 5, 2018
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Neuroscientist Dr. David Vilchez and his team at CECAD, the University of Cologne's Cluster of Excellence for Aging Research, have made an important step toward understanding the mechanisms that cause the neurodegenerative ...
Jul 27, 2018
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McMaster University researchers have developed a new theory on Huntington's disease which is being welcomed for showing promise to open new avenues of drug development for the condition.
Jul 9, 2018
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