Neuroscience
First patients dosed with 'gene silencing' drug for Huntington's disease
The first few patients have received doses of an experimental RNA-targeting drug for Huntington's disease, it was announced today.
Oct 19, 2015
0
12383
News tagged with huntingtin
Neuroscience
CRISPR/Cas9 gene editing reverses Huntington's in mouse model
Disrupting a problematic gene in brain cells can reverse Huntington's disease pathology and motor symptoms in a mouse model of the inherited neurological disorder, scientists report.
Jun 19, 2017
0
1699
Neuroscience
Scientists move closer to treatment for Huntington's disease
A new variant of the gene-editing CRISPR/Cas9 system is safer and more specific than versions previously used in early research towards a treatment for Huntington's disease, shows research published today in Frontiers in ...
Feb 26, 2018
0
6
Neuroscience
Scientists develop therapeutic protein, protect nerve cells from Huntington's Disease
A new scientific study reveals one way to stop proteins from triggering an energy failure inside nerve cells during Huntington's disease. Huntington's disease is an inherited genetic disorder caused by mutations in the gene ...
Sep 13, 2016
0
1010
Neuroscience
Researchers discover system that could reduce neurodegeneration in Huntington's disease
Neuroscientist Dr. David Vilchez and his team at CECAD, the University of Cologne's Cluster of Excellence for Aging Research, have made an important step toward understanding the mechanisms that cause the neurodegenerative ...
Jul 27, 2018
0
121
Neuroscience
Toxic protein build-up in blood shines light on Huntington's disease
A new light-based technique for measuring levels of the toxic protein that causes Huntington's disease (HD) has been used to demonstrate that the protein builds up gradually in blood cells. Published today in the Journal ...
Sep 17, 2012
0
0
Neuroscience
New insight into Huntington's disease may open door to drug development
McMaster University researchers have developed a new theory on Huntington's disease which is being welcomed for showing promise to open new avenues of drug development for the condition.
Jul 9, 2018
0
176
Genetics
Huntington's disease protein controls movement of precious cargo inside cells, study finds
We've known for years that the Huntingtin protein (Htt) is responsible for Huntington's disease, a neurodegenerative disorder that diminishes a person's mental and physical abilities.
Oct 16, 2015
0
107
Neuroscience
New roles found for Huntington's disease protein
A Duke University research team has identified a new function of a gene called huntingtin, a mutation of which underlies the progressive neurodegenerative disorder known as Huntington's Disease.
Jan 21, 2020
0
80
Neuroscience
Scientists uncover major factor in development of Huntington's disease
Scientists from the Florida campus of The Scripps Research Institute (TSRI) have uncovered a major contributor to Huntington's disease, a devastating progressive neurological condition that produces involuntary movements, ...
Oct 28, 2014
0
0
