Immunology

Toxin floats on lipid rafts

Helicobacter pylori, the leading cause of peptic ulcer disease and stomach cancer. One factor important to H. pylori infection is the pore-forming toxin VacA. It is thought to gain entry into host cells by binding to specialized ...

Psychology & Psychiatry

Is ketamine a panacea for depression?

Researchers have long been intrigued by the antidepressant qualities of the club drug ketamine. Known on the street as "Special K," the drug is taken by partiers for its brief dissociative hallucinogenic effect, but it is ...

Cancer

New mechanobiology technique to stop cancer cell migration

Researchers at the Okinawa Institute of Science and Technology Graduate university (OIST) have developed a novel technique that stops cervical cancer cell migration. The research, published in Chem could open up new avenues ...

Medical research

Lipid deficiency linked to neuron degeneration

A type of lipid that naturally declines in the aging brain impacts – within laboratory models used to study Parkinson's disease – a protein associated with the disease, according to a study co-authored by University of ...

Medical research

Cholesterol sets off chaotic blood vessel growth

A study at the University of California, San Diego School of Medicine identified a protein that is responsible for regulating blood vessel growth by mediating the efficient removal of cholesterol from the cells. Unregulated ...

Alzheimer's disease & dementia

Alzheimer's protein structure offers new treatment directions

The molecular structure of a protein involved in Alzheimer's disease – and the surprising discovery that it binds cholesterol – could lead to new therapeutics for the disease, Vanderbilt University investigators ...

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