Medical research

Tackling liver injury

A new drug spurs liver regeneration after surgery, according to a paper published in The Journal of Experimental Medicine.

Medical research

Aberrant mTOR signaling impairs whole body physiology

The protein mTOR is a central controller of growth and metabolism. Deregulation of mTOR signaling increases the risk of developing metabolic diseases such as diabetes, obesity and cancer. In the current issue of the journal ...

Oncology & Cancer

A possible pathway for inhibiting liver and colon cancer is found

A group of scientists from Spain, the UK and the United States has revealed the structure of a protein complex involved in liver and colon cancers. Both of these types of cancer are of significant social and clinical relevance ...

Neuroscience

Fatal cellular malfunction identified in Huntington's disease

Researchers believe they have learned how mutations in the gene that causes Huntington's disease kill brain cells, a finding that could open new opportunities for treating the fatal disorder. Scientists first linked the gene ...

Medical research

Unexpected player in regulation of blood cholesterol levels

Kinesins are motor proteins that "walk" along microtubules and transport various cargoes throughout the cell. A study in The Journal of Cell Biology uncovers an unexpected role for one kinesin in the pathway that regulates ...

Overweight & Obesity

Protein maybe key to halting obesity related disease

(Medical Xpress)—Australians are getting more obese and developing a disease called non-alcoholic fatty liver disease – a disease similar to that that results in cirrhosis in alcoholics and can be a precursor to diabetes.

Medical research

The internal clock and feeding rhythm set the pace of the liver

Living organisms have adapted to the day-night cycle and, in most cases, they have evolved a "circadian clock". Its effects are not completely known yet but its functioning has been shown to have important metabolic consequences ...

Medical research

Surprising discovery: The skin communicates with the liver

Researchers from the University of Southern Denmark have discovered that the skin is capable of communicating with the liver. The discovery has surprised the scientists, and they say that it may help our understanding of ...

Immunology

Liver tropism is key for B cell deletion immunotherapy

Antibodies against the B cell surface protein CD20 have been used successfully to treat B cell-mediated autoimmune diseases and lymphomas. Antibody binding receptors, called Fc receptors, on other immune cells bind anti-CD20 ...

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