Immunology

Regulatory and effector B cells control scleroderma

Systemic sclerosis (SSc, also known as scleroderma), a connective tissue disorder of autoimmune etiology, is characterized by excessive fibrosis in the skin and various internal organs. More than 90 percent of SSc patients ...

Diseases, Conditions, Syndromes

Metformin reverses established lung fibrosis

Researchers at the University of Alabama at Birmingham have shown—for the first time—that established lung fibrosis can be reversed using a drug treatment that targets cell metabolism.

Diseases, Conditions, Syndromes

Bacterial conversations in cystic fibrosis

"A large part of my research is thinking about how bacteria communicate," says Sophie Darch. The postdoctoral researcher works with School of Biological Sciences Professor Marvin Whiteley, studying the social lives of bacteria.

Diseases, Conditions, Syndromes

Lung-on-a-chip simulates pulmonary fibrosis

Developing new medicines to treat pulmonary fibrosis, one of the most common and serious forms of lung disease, is not easy.

Medical research

Lung diseases share molecular signature

The fibrotic lung diseases BPD (bronchopulmonary dysplasia) and IPF (idiopathic pulmonary fibrosis) affect preterm infants and older adults, respectively. Evidence suggests that these diseases involve dysregulation of lung ...

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