Medical research
Cellular hitchhikers may hold a key to understanding ALS
For long-distance transportation within the cell, RNA molecules rely on hitchhiking.
Sep 19, 2019
0
44
News tagged with lysosomes
Medical research
Researchers solve mystery surrounding a form of Batten disease
A team led by researchers at Baylor College of Medicine has uncovered an unexpected mechanism that can explain a form of Batten disease called neuronal ceroid lipofuscinosis 8. The findings published in the journal Nature ...
Nov 5, 2018
0
150
Oncology & Cancer
Study shows how to make (and destroy) a metastatic cancer cell
Many cancers become especially dangerous only when they metastasize from their site of origin to faraway tissues such as lung, brain or bone. Now, a University of Colorado Cancer Center study published today in the Proceedings ...
Aug 20, 2018
0
140
Genetics
Gene loss can lead to accumulation of waste products in cells
MIT biologists have discovered a function of a gene that is believed to account for up to 40 percent of all familial cases of amyotrophic lateral sclerosis (ALS). Studies of ALS patients have shown that an abnormally expanded ...
May 7, 2018
0
50
Parkinson's & Movement disorders
Mechanism behind common Parkinson's mutation discovered
Northwestern Medicine investigators have discovered how a gene mutation results in buildup of a toxic compound known to cause Parkinson's disease symptoms, defining for the first time the mechanism underlying that aspect ...
Feb 5, 2018
0
352
Neuroscience
Granulins are brain treasure, not trash
Emory University School of Medicine researchers have developed tools that enable them to detect small proteins called granulins for the first time inside cells. Granulins are of interest to neuroscientists because mutations ...
Aug 14, 2017
0
58
Immunology
Nature study suggests new therapy for Gaucher disease
Scientists propose in Nature blocking a molecule that drives inflammation and organ damage in Gaucher and maybe other lysosomal storage diseases as a possible treatment with fewer risks and lower costs than current therapies.
Feb 22, 2017
0
2
Medical research
Research reveals strategy to potentially treat juvenile Batten disease
Researchers at Baylor College of Medicine, Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital and King's College London have discovered a treatment that improves the neurological symptoms in a ...
Feb 6, 2017
0
56
Oncology & Cancer
Tumors hijack export pathway in cells to resist chemotherapy and fuel disease progression
St. Jude Children's Research Hospital scientists have discovered how an aggressive tumor of the muscle and soft tissue hijacks an export pathway in cells to lay the groundwork for cancer progression and resistance to chemotherapy. ...
Dec 21, 2015
0
64
Genetics
Batten disease may benefit from gene therapy
In a study of dogs, scientists showed that a new way to deliver replacement genes may be effective at slowing the development of childhood Batten disease, a rare and fatal neurological disorder. The key may be to inject viruses ...
Nov 11, 2015
0
427
