Genetics

In cancer, an embryonic gene-silencing mechanism gone awry

There are some genes that are only activated in the very first days of an embryo's existence. Once they have accomplished their task, they are shut down forever, unlike most of our genes, which remain active throughout our ...

Oncology & Cancer

Scientists use worms to unearth cancer drug targets

Through novel experiments involving small nematode worms, scientists from Wyoming have discovered several genes that may be potential targets for drug development in the ongoing war against cancer. Specifically, researchers ...

Oncology & Cancer

Researchers find driver of breast cancer stem cell metastasis

The finding involves the cancer gene RhoC, which has previously been shown to promote metastasis of many types of cancer. RhoC levels increase as breast cancer progresses and high levels of RhoC are associated with worse ...

Oncology & Cancer

WHO's cancer agency: Diesel fumes cause cancer

Diesel exhaust causes cancer, the World Health Organization's cancer agency declared Tuesday, a ruling it said could make exhaust as important a public health threat as secondhand smoke.

Medical research

Compound that halts growth of malaria parasite created

A drug candidate that has shown promise for neutralizing dangerous bacteria also prevents the parasite that causes malaria from growing, new research by a Yale University team headed by Nobel laureate Sidney Altman shows.

Genetics

Preventing dangerous nonsense in human gene expression

Human genes are preferentially encoded by codons that are less likely to be mistranscribed (or "misread") into a STOP codon. This finding by Brian Cusack and colleagues from the Max Planck Institute for Molecular Genetics ...

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