Oncology & Cancer

3-D biopsies to better understand brain tumors

Researchers at the Institut de Neurociències of the Universitat Autònoma de Barcelona (INc-UAB) obtained a highly accurate recreation of human glioblastoma's features using a novel 3-D microscopy analysis. The study, published ...

Oncology & Cancer

Reviving exhausted immune cells to fight cancer

Eliminating a single gene can turn exhausted cancer-fighting immune cells known as CD8+ T cells back into refreshed soldiers that can continue to battle malignant tumors, a new study led by UT Southwestern researchers suggests. ...

Oncology & Cancer

A new, potent weapon against lymphomas

MDC researchers have developed a new approach to CAR T-cell therapy. The team has shown in Nature Communications that the procedure is very effective, especially when it comes to fighting follicular lymphomas and chronic ...

Oncology & Cancer

Apoptosis inhibitor enables some lymphomas to resist therapy

Lymphomas are a diverse group of cancers of the immune system, which is the body's primary defense against autoimmune disease, infections, and malignancy. Now, researchers at the University of Tsukuba have clarified risk ...

Oncology & Cancer

Attacking tumors from the inside

A new technology that allows researchers to peer inside malignant tumors shows that two experimental drugs can normalize aberrant blood vessels, oxygenation, and other aspects of the tumor microenvironment in non-small cell ...

Oncology & Cancer

Adverse effects from cancer drug trials explained

A team of researchers investigating how a certain type of drugs can kill cells has discovered that these drugs can do more harm than good when used in combination with other cancer treatments.

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Malignancy

Malignancy (from the Latin roots mal- = "bad" and -genus = "born") is the tendency of a medical condition, especially tumors to become progressively worse and to potentially result in death. It is characterized by the properties of anaplasia, invasiveness, and metastasis. Malignant is a corresponding adjectival medical term used to describe a severe and progressively worsening disease. The term is most familiar as a description of cancer. A malignant tumor may be contrasted with a non-cancerous benign tumor in that a malignancy is not self-limited in its growth, is capable of invading into adjacent tissues, and may be capable of spreading to distant tissues (metastasizing), while a benign tumor has none of those properties. Malignant tumor is synonymous with cancer. Uses of "malignant" in oncology:

Non-oncologic disorders referred to as "malignant":

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