Sensory neurons play a crucial role in the perception of "hot" and "cold". They express a group of ion channels called thermosensitive TRP channels. For example, TRPV1 (activated above 43°C) and TRPM8 (activated below 29°C) ...
Jul 21, 2023
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The specific or acquired immune system of vertebrates is a powerful weapon against pathogens and pathologically altered body cells. Here, T cells play a special role. After activation, they can systematically kill off target ...
Jul 13, 2023
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Researchers at Children's Hospital of Philadelphia (CHOP) have identified a molecule that plays a role in post-translational modification and activation in myeloid malignancies, making it a potential therapeutic target. The ...
Jun 16, 2023
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Researchers have for the first time characterized a unique molecular mechanism of the early stages of programmed cell death or apoptosis, a process which plays a crucial role in prevention of cancer.
Jun 2, 2023
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A common feature of many neurodegenerative diseases are pathological protein deposits in the brain. These protein aggregates cause nerve cells to die and, as a result, entire brain areas to shrink, which manifests in affected ...
May 25, 2023
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Lung cancer claims more lives each year than any other type of cancer worldwide. According to the World Health Organization, an estimated 1.8 million people died of lung cancer in 2020. Current treatments rely on one of two ...
Feb 1, 2023
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NeuroOmics technology lets researchers label and capture cell-surface proteins in intact, live tissue—opening opportunities to understand complex cellular interactions and future drug targets.
Oct 19, 2022
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A Northwestern Medicine study has identified a protein that drives breast cancer stemness and metastasis. The findings, enabled by machine learning, were published in the journal eLife.
Oct 17, 2022
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University of Alberta research shows how cell membranes play a much larger role than previously understood in allowing spike proteins on viruses to infect cells. The findings, published in the journal iScience, could give ...
Sep 16, 2022
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A lipid found in the membranes of neurons may play a fundamental role in the development and progression of Alzheimer's disease, according to a study by Penn State College of Medicine researchers. Their findings, published ...
Aug 19, 2022
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