Immunology

Toxin floats on lipid rafts

Helicobacter pylori, the leading cause of peptic ulcer disease and stomach cancer. One factor important to H. pylori infection is the pore-forming toxin VacA. It is thought to gain entry into host cells by binding to specialized ...

Oncology & Cancer

Ras protein's role in spreading cancer

Protein systems, such as Ras, make up the complex signaling pathways that control whether a cell divides or, in some cases, becomes cancerous and metastasizes into other regions of the body. For example, 98 percent of pancreatic ...

Neuroscience

Researchers study cellular processes dependent on calcium ions

Calcium-ATPases convey calcium ions (Ca2+) from the cytoplasm to the extracellular space via active transport (using ATP as an energy source), and thus fundamentally contribute to the control of a wide variety of Ca2+-dependent ...

Parkinson's & Movement disorders

On the trail of Parkinson's disease

The molecular causes of diseases such as Parkinson's need to be understood as a first step towards combating them. University of Konstanz chemists working alongside Professor Malte Drescher recently succeeded in analysing ...

Diseases, Conditions, Syndromes

Computer simulations reveal every curve of the dengue viral envelope

The near-spherical outer structure of the dengue virus has been recreated in remarkable detail by a team of bioinformaticians in Singapore. The virtual model could show researchers how the virus fuses with and infects human ...

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