Neuroscience

Hypothalamus neurons modulate pancreatic insulin amounts

The brain is key in the regulation of appetite, body weight and metabolism. Specifically, there is a small group of POMC neurons in the hypothalamus that detect and integrate signals related to the body's energy state and ...

Medical research

Molecular corkscrew

Scientists from the universities of Zurich and Duisburg-Essen have discovered a specific function of the protein p97/VCP. They demonstrate that the protein repairs DNA breaks like a corkscrew, a repair mechanism that could ...

Diseases, Conditions, Syndromes

Study finds clue to birth defects in babies of mothers with diabetes

In a paper published today in Diabetologia, a team at Joslin Diabetes Center, headed by Mary R. Loeken, PhD, has identified the enzyme AMP kinase (AMPK) as key to the molecular mechanism that significantly increases the risk ...

Oncology & Cancer

Chemists determine one way tumors meet their growing need

Behaving something like ravenous monsters, tumors need plentiful supplies of cellular building blocks such as amino acids and nucleotides in order to keep growing at a rapid pace and survive under harsh conditions. How such ...

Medical research

Micro-control of liver metabolism

Researchers at TIFR have discovered molecular anticipation of feeding in the liver that is essential to ensure that the body, after fasting, adapts to use incoming nutrients upon re-feeding. Their findings, published in the ...

Genetics

Epigenetics and epidemiology -- hip, hype and science

Epigenetics is the new hip science. Time Magazine's front cover and article, 'Why your DNA isn't your Destiny' from January 2010 explains why. Its more explicit subtitle provided the hook - 'The new science of epigenetics ...

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